What is a potential side effect common among SSRIs?

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A common side effect associated with selective serotonin reuptake inhibitors (SSRIs) is serotonin syndrome. This condition arises when there is an excess of serotonin in the brain, which can occur when SSRIs are taken alone or in combination with other medications that increase serotonin levels. Symptoms of serotonin syndrome can range from mild changes in mental status, such as confusion or agitation, to severe symptoms like hyperthermia, muscle rigidity, and seizures. Recognizing this potential side effect is crucial for healthcare providers and patients to ensure timely intervention if it occurs.

While weight loss can occur with some SSRIs and elevated heart rate may be a concern with various medications, these are not the hallmark risks associated with SSRIs as a class. Similarly, high blood pressure is not a typical side effect of SSRIs, although some individuals may experience changes in blood pressure due to various factors. Thus, serotonin syndrome stands out as a significant and specific concern related to the mechanism of action of SSRIs.

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